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Article

Caffeine modulates glucocorticoid-induced expression of CTGF in lung epithelial cells and fibroblasts

23 Mar 2017

Abstract excerpt

BACKGROUND: Although caffeine and glucocorticoids are frequently used to treat chronic lung disease in preterm neonates, potential interactions are largely unknown. While anti-inflammatory effects of glucocorticoids are well defined, their impact on airway remodeling is less characterized. Caffeine has been ascribed to positive effects on airway inflammation as well as remodeling. Connective tissue growth factor...

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PMID: 28330503
DOI: 10.1186/s12931-017-0535-8

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