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Article

Piezo1 induced apoptosis of type II pneumocytes during ARDS

11 Jun 2019

Abstract excerpt

OBJECTIVE: The mechanisms of lung injury in acute respiratory distress syndrome (ARDS) are not well understood.Piezo1 was recently identified as a mechanotransduction protein. The present study found the expression of Piezo1 in type II pneumocytes and investigated its role in mediating ARDS-related lung injury. METHODS: Sprague-Dawley rats were used to establish an ARDS model, the expression of Piezo1,lung...

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PMID: 31186017
DOI: 10.1186/s12931-019-1083-1

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