Article
The emergence of 'hypervirulence' in Clostridium difficile.
International journal of medical microbiology : IJMM - 1 Aug 2010
Cartman Stephen T, Heap John T, Kuehne Sarah A, Cockayne Alan, Minton Nigel P
Abstract excerpt
The impact of Clostridium difficile-associated disease (CDAD) in healthcare settings throughout the developed world is considerable in terms of mortality, morbidity, and disease management. The incidence of CDAD has risen dramatically since the turn of this century, concomitant with the emergence of so-called hypervirulent strains which are thought to cause a more severe disease, higher relapse rates, and...
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