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Article

Lack of association of tcdC type and binary toxin status with disease severity and outcome in toxigenic Clostridium difficile.

The Journal of infection - 1 May 2011

Goldenberg Simon D, French Gary L

Abstract excerpt

The production of binary toxin and presence of truncating mutations in the putative toxin repressor gene, tcdC, have been associated with the increased virulence and spread of Clostridium difficile, especially ribotype 027. We analysed the prevalence of binary toxin genes and tcdC mutations in 207 clinical C. difficile isolates collected between 2008-2010. The majority (83%) belonged to one of five tcdC types and...

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Identifiers

PMID: 21396957
DOI: 10.1016/j.jinf.2011.03.001

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