Article
Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium.
Genome biology - 1 Jan 2009
Stabler Richard A, He Miao, Dawson Lisa, Martin Melissa, Valiente Esmeralda, Corton Craig, Lawley Trevor D, Sebaihia Mohammed, Quail Michael A, Rose Graham, Gerding Dale N, Gibert Maryse, Popoff Michel R, Parkhill Julian, Dougan Gordon, Wren Brendan W
Abstract excerpt
BACKGROUND: The continued rise of Clostridium difficile infections worldwide has been accompanied by the rapid emergence of a highly virulent clone designated PCR-ribotype 027. To understand more about the evolution of this virulent clone, we made a three-way genomic and phenotypic comparison of...
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