Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphism of xenobiotic-metabolizing genes and breast cancer susceptibility in North Indian women.

Genetic testing and molecular biomarkers - 1 May 2011

Singh Virendra, Upadhyay Ghanshyam, Rastogi Neeraj, Singh Kalpana, Singh Mahendra Pratap

Abstract excerpt

NAD(P)H:quinone oxidoreductase 1 (NQO1) and cytochrome P450 1A2 (CYP1A2) are involved in the metabolism of estrogens. Genetic polymorphisms in these genes may lead to interindividual variation in breast cancer susceptibility. This study was undertaken to investigate the association of NQO1 exon 6 proline187serine (C609T) and CYP1A2 exon 2 phenylalanine21leucine (C63G) polymorphisms with breast cancer...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to NQO1 gene

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genotype

Share to NAD(P)H Dehydrogenase (Quinone)

Share to Polymorphism, Single Nucleotide

Share to White People

Source

Identifiers

PMID: 21329464
DOI: 10.1089/gtmb.2010.0197

Genes

NQO1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphism of xenobiotic-metabolizing genes and breast cancer susceptibility in North Indian women.PMID 21329464Read ↗

The C609T (Pro187Ser) Null Polymorphism of the NQO1 Gene Contributes Significantly to Breast Cancer Susceptibility in North Indian Populations: a Case Control Study.Semantic proximity Read ↗

The NQO1 Pro187Ser polymorphism and breast cancer susceptibility: evidence from an updated meta-analysis.Semantic proximity Read ↗

A study on the association of cytochrome-P450 1A1 polymorphism and breast cancer risk in north Indian women.Semantic proximity Read ↗

Impact of xenobiotic-metabolizing gene polymorphisms on breast cancer risk in South Indian women.Semantic proximity Read ↗

Evidence on the association between NQO1 Pro187Ser polymorphism and breast cancer risk in the current studies: a meta-analysis.Semantic proximity Read ↗

NAD(P)H:quinone oxidoreductase 1 Arg139Trp and Pro187Ser polymorphisms imbalance estrogen metabolism towards DNA adduct formation in human mammary epithelial cells.Semantic proximity Read ↗

Genetic polymorphisms of estrogen metabolizing enzyme and breast cancer risk in Thai women.Semantic proximity Read ↗

NAD(P)H:quinone oxidoreductase: polymorphisms and allele frequencies in Caucasian, Chinese and Canadian Native Indian and Inuit populations.Semantic proximity Read ↗

Genetic polymorphisms in estrogen metabolism and breast cancer risk in case-control studies in Japanese, Japanese Brazilians and non-Japanese Brazilians.Semantic proximity Read ↗

Functional polymorphisms, altered gene expression and genetic association link NRH:quinone oxidoreductase 2 to breast cancer with wild-type p53.Semantic proximity Read ↗

Genetic variants in metabolizing genes NQO1, NQO2, MTHFR and risk of prostate cancer: a study from North India.Semantic proximity Read ↗

NAD(P)H:quinone oxidoreductase 1 (NQO1) Pro187Ser polymorphism and colorectal cancer predisposition in the ethnic Kashmiri population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.