Article
Genetic polymorphisms in estrogen metabolism and breast cancer risk in case-control studies in Japanese, Japanese Brazilians and non-Japanese Brazilians.
Journal of human genetics - 1 Apr 2009
Shimada Naoki, Iwasaki Motoki, Kasuga Yoshio, Yokoyama Shiro, Onuma Hiroshi, Nishimura Hideki, Kusama Ritsu, Hamada Gerson Shigeaki, Nishimoto Ines Nobuko, Iyeyasu Hirofumi, Motola Juvenal, Laginha Fábio Martins, Kurahashi Norie, Tsugane Shoichiro
Abstract excerpt
Although many studies have examined associations between single nucleotide polymorphisms (SNPs) in the CYP1A1, CYP1A2 and CYP1B1 genes and breast cancer risk, no study has examined functional SNPs in the CYP3A5 gene and only a small number of studies have been investigated in Japanese populations. To examine the association between six SNPs, CYP1A1(*)2A, CYP1A1(*)2C, CYP1A2(*)1F, CYP1B1 Arg(48)Gly, CYP1B1...
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