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Article

Partial rescue of the phenotype in 1α-hydroxylase gene knockout mice by vitamin D3 injection.

Endocrine research - 1 Jan 2011

Zhang Zeng-Li, Ding Xiao-Fei, Tong Jian, Li Bing-Yan

Abstract excerpt

OBJECTIVE: To investigate whether 25-hydroxyvitamin D [25(OH)D] can mediate effects without being converted to 1α,25-dihydroxyvitamin D [1,25(OH)2D]. METHODS: Vitamin D3 (VD3) was injected intramuscularly to 25-hydroxyvitamin D-1α-hydroxylase [1α(OH)ase] gene knockout (KO) male mice with a dose of 10,000 IU per week for 4 weeks. Skeleton Parameters and Serum biochemistry in mice were assayed. RESULTS: Serum...

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Identifiers

PMID: 21329450
DOI: 10.3109/07435800.2010.542415

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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