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Article

Preferential deletion events in the direct repeat locus of Mycobacterium tuberculosis.

Journal of clinical microbiology - 1 Apr 2011

Schürch Anita C, Kremer Kristin, Kiers Albert, Boeree Martin J, Siezen Roland J, van Soolingen Dick

Abstract excerpt

The "Harlingen" IS6110 restriction fragment length polymorphism (RFLP) cluster has linked over 100 tuberculosis cases in The Netherlands since 1993. Four Mycobacterium tuberculosis isolates that were epidemiologically linked to this cluster had different spoligotype patterns, as well as slightly divergent IS6110 profiles, compared to the majority of the isolates. Sequencing of the direct repeat (DR) locus...

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Identifiers

PMID: 21325559
DOI: 10.1128/JCM.01848-10
PMCID: PMC3122804

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