Article
Occurrence and Nature of Double Alleles in Variable-Number Tandem-Repeat Patterns of More than 8,000 Mycobacterium tuberculosis Complex Isolates in The Netherlands.
Journal of clinical microbiology - 1 Feb 2018
Jajou Rana, Kamst Miranda, van Hunen Rianne, de Zwaan Carolina Catherina, Mulder Arnout, Supply Philip, Anthony Richard, van der Hoek Wim, van Soolingen Dick
Abstract excerpt
Since 2004, variable-number tandem-repeat (VNTR) typing of Mycobacterium tuberculosis complex isolates has been applied on a structural basis in The Netherlands to study the epidemiology of tuberculosis (TB). Although this technique is faster and technically less demanding than the previously used restriction fragment length polymorphism (RFLP) typing, reproducibility remains a concern. In the period from 2004 to...
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