Article
CTCF and BORIS Regulate <i>Rb2/p130</i> Gene Transcription: A Novel Mechanism and a New Paradigm for Understanding the Biology of Lung Cancer
1 Feb 2011
Abstract excerpt
Although innumerable investigations regarding the biology of lung cancer have been carried out, many aspects thereof remain to be addressed, including the role played by the retinoblastoma-related protein Rb2/p130 during the evolution of this disease. Here we report novel findings on the mechanisms that control Rb2/p130 gene expression in lung fibroblasts and characterize the effects of Rb2/p130 deregulation on...
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