Coat colour phenotype, leucopenia, and insulin-dependent diabetes mellitus (IDDM) in BB rats.

Article

Coat colour phenotype, leucopenia, and insulin-dependent diabetes mellitus (IDDM) in BB rats.

Diabetes research (Edinburgh, Scotland) - 1 Sept 1990

Kloeting I, Vogt L

Abstract excerpt

Susceptibility to IDDM in BB rats is linked to the MHC and to one or two non-MHC genes. It is postulated that one of the non-MHC genes is leucopenia inherited as autosomal recessive trait which is, at least in part, due to the absence of RT6.1 T lymphocyte subsets. Because the RT6 alloantigenic s...

Topics

Animals
Crosses, Genetic
Diabetes Mellitus, Experimental
Diabetes Mellitus, Type 1
Female
Genetic Predisposition to Disease
Hair Color
Haplotypes
Insulin
Islets of Langerhans
Leukopenia
Male
Phenotype
Rats
Rats, Inbred BB

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