Article
The role of N-acetyltransferase 2 polymorphism in the etiopathogenesis of inflammatory bowel disease.
Digestive diseases and sciences - 1 Jul 2011
Baranska M, Trzcinski R, Dziki A, Rychlik-Sych M, Dudarewicz M, Skretkowicz J
Abstract excerpt
BACKGROUND AND PURPOSE: Inflammatory bowel disease (IBD) consists of ulcerative colitis (UC) and Crohn's disease (CD), which are complex genetic disorders resulting from the interplay between several genetic and environmental risk factors. The arylamine N-acetyltransferase 2 (NAT2) enzyme detoxifies a wide spectrum of naturally occurring xenobiotics including carcinogens and drugs. Acetylation catalyzed by NAT2...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
