Article
Crohn's disease in Japanese is associated with a SNP-haplotype of N-acetyltransferase 2 gene.
World journal of gastroenterology - 21 Aug 2005
Machida Haruhisa, Tsukamoto Kazuhiro, Wen Chun-Yang, Shikuwa Saburou, Isomoto Hajime, Mizuta Yohei, Takeshima Fuminao, Murase Kunihiko, Matsumoto Naomichi, Murata Ikuo, Kohno Shigeru, Wen Chen-Yang
Abstract excerpt
AIM: To investigate the frequency and distribution of N-acetyltransferase 2 (NAT2) and uridine 5'-diphosphate (UDP)-glucuronosyltransferase 1A7 (UGT1A7) genes in patients with ulcerative colitis (UC) and Crohn's disease (CD). METHODS: Frequencies and distributions of NAT2 and UGT1A7 SNPs as well as their haplotypes were investigated in 95 patients with UC, 60 patients with CD, and 200 gender-matched, unrelated,...
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