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The N-Acetyltransferase 2 Polymorphism and Susceptibility to Inflammatory Bowel Disease: A Case-Control Study.

Pharmacology research & perspectives - 1 Feb 2025

Petryszyn Pawel, Zurakowski Grzegorz, Dudkowiak Robert, Machowska Marta, Gruca Agnieszka, Ekk-Cierniakowski Pawel, Skretkowicz Jadwiga, Poniewierka Elzbieta, Wiela-Hojenska Anna, Glowacka Krystyna

Abstract excerpt

The enzyme N-acetyltransferase 2 (NAT2) plays an important role in metabolism and detoxification of xenobiotics, including carcinogens and medications. We aimed to assess the contribution of the NAT2 polymorphism to susceptibility to inflammatory bowel disease (IBD) in the Polish population. The study involved 101 IBD patients and 100 healthy controls. The NAT2 gene mutations at positions 481T, 803G, 590A, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39720855
DOI: 10.1002/prp2.70040
PMCID: PMC11669041

Genes

NAT2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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