Article
Implications of macrophage polarization in autoimmunity.
Immunology - 1 Jun 2018
Funes Samanta C, Rios Mariana, Escobar-Vera Jorge, Kalergis Alexis M
Abstract excerpt
Macrophages are extremely heterogeneous and plastic cells with an important role not only in physiological conditions, but also during inflammation (both for initiation and resolution). In the early 1990s, two different phenotypes of macrophages were described: one of them called classically activated (or inflammatory) macrophages (M1) and the other alternatively activated (or wound-healing) macrophages (M2)....
Topics
- Animals
- Autoimmune Diseases
- Autoimmunity
- Cytokines
- Heme Oxygenase (Decyclizing)
- Humans
- Immunoglobulins, Intravenous
- Inflammation Mediators
- Macrophage Activation
- Macrophages
- Phenotype