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Article

The functional -374T/A polymorphism of the receptor for advanced glycation end products may modulate Crohn's disease.

American journal of physiology. Gastrointestinal and liver physiology - 1 May 2011

Däbritz Jan, Friedrichs Frauke, Weinhage Toni, Hampe Jochen, Kucharzik Torsten, Lügering Andreas, Broeckel Ulrich, Schreiber Stefan, Spieker Tilmann, Stoll Monika, Foell Dirk

Abstract excerpt

The receptor for advanced glycation end products (RAGE) is involved in innate immune mechanisms. Polymorphisms of the RAGE gene have been described as a factor amplifying inflammation in susceptible patients, but the association with Crohn's disease (CD) is not known. The coding RAGE polymorphism G82S (rs2070600) and two promoter polymorphisms, -374T/A (rs1800624) and -429T/C (rs1800625), were studied in two...

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PMID: 21311028
DOI: 10.1152/ajpgi.00115.2010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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