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Article

LDOC1 mRNA is differentially expressed in chronic lymphocytic leukemia and predicts overall survival in untreated patients.

Blood - 14 Apr 2011

Duzkale Hatice, Schweighofer Carmen D, Coombes Kevin R, Barron Lynn L, Ferrajoli Alessandra, O'Brien Susan, Wierda William G, Pfeifer John, Majewski Tadeusz, Czerniak Bogdan A, Jorgensen Jeffrey L, Medeiros L Jeffrey, Freireich Emil J, Keating Michael J, Abruzzo Lynne V

Abstract excerpt

We previously identified LDOC1 as one of the most significantly differentially expressed genes in untreated chronic lymphocytic leukemia (CLL) patients with respect to the somatic mutation status of the immunoglobulin heavy-chain variable region genes. However, little is known about the normal function of LDOC1, its contribution to the pathophysiology of CLL, or its prognostic significance. In this study, we have...

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Source

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Identifiers

PMID: 21310924
DOI: 10.1182/blood-2010-09-304881
PMCID: PMC3087532

Genes

LDOC1
ZAP70

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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