Article
CLLU1 expression has prognostic value in chronic lymphocytic leukemia after first-line therapy in younger patients and in those with mutated IGHV genes.
Haematologica - 1 Feb 2013
Gonzalez David, Else Monica, Wren Dorte, Usai Monica, Buhl Anne Mette, Parker Anton, Oscier David, Morgan Gareth, Catovsky Daniel
Abstract excerpt
CLLU1, located at chromosome 12q22, encodes a transcript specific to chronic lymphocytic leukemia and has potential prognostic value. We assessed the value of CLLU1 expression in the LRF CLL4 randomized trial. Samples from 515 patients with chronic lymphocytic leukemia were collected immediately...
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