Article
Overexpression of Sterol Carrier Protein 2 in patients with hereditary cholesterol gallstones.
BMC gastroenterology - 10 Feb 2011
Cui YunFeng, Li ZhongLian, Zhao ErPeng, Jia YanFeng, Li DongHua, Zhang Ju, Cui NaiQiang
Abstract excerpt
BACKGROUND: Lithogenic bile is the major cause of cholesterol gallstone, but its pathogenesis is not well understood. The hypersecretion of biliary cholesterol is believed to be an important cause of lithogenic bile. Sterol Carrier Protein 2 (SCP2) participates in cholesterol trafficking and lipid metabolism in hepatocytes and may play a key role in cholesterol gallstone formation. METHODS: 21 cholesterol...
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