Article
Association of polymorphisms in the solute carrier organic anion transporter family member 1B1 gene with essential hypertension in the Uyghur population.
Annals of human genetics - 1 Mar 2011
Lin Rong, Wang Xiaofeng, Zhou Weichen, Fu Wenqing, Wang Ying, Huang Wei, Jin Li
Abstract excerpt
Solute carrier organic anion transporter family member 1B1 (SLCO1B1) is an important hepatic uptake transporter that can transport a wide variety of endogenous compounds, including thyroid hormones and prostaglandin E2. Dysregulation of thyroid hormones and prostaglandin E2 plays a role in the development of hypertension, suggesting that SLCO1B1 might contribute to the aetiology of essential hypertension (EH). In...
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