Article
Haplotype-based case-control study of the association between the guanylate cyclase activator 2B (GUCA2B, Uroguanylin) gene and essential hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Sept 2007
Yoshikawa Yukie, Nakayama Tomohiro, Saito Kosuke, Hui Peng, Morita Akihiko, Sato Naoyuki, Takahashi Teruyuki, Tamura Masaaki, Sato Ichiro, Aoi Noriko, Doba Nobutaka, Hinohara Shigeaki, Soma Masayoshi, Usami Ron
Abstract excerpt
Uroguanylin (gene name: guanylate cyclase activator 2B, GUCA2B) is a peptide regulator of intestinal salt and water transport. It has been reported that the uroguanylin knockout mouse exhibits elevated blood pressure. Therefore, the GUCA2B gene is thought to be a susceptibility gene for essential hypertension (EH). Despite extensive studies, however, the relationship between the GUCA2B gene and EH has not yet...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.