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Article

Relationship between genomic distance-based regression and kernel machine regression for multi-marker association testing.

Genetic epidemiology - 1 May 2011

Pan Wei

Abstract excerpt

To detect genetic association with common and complex diseases, two powerful yet quite different multimarker association tests have been proposed, genomic distance-based regression (GDBR) (Wessel and Schork [2006] Am J Hum Genet 79:821–833) and kernel machine regression (KMR) (Kwee et al. [2008] Am J Hum Genet 82:386–397; Wu et al. [2010] Am J Hum Genet 86:929–942). GDBR is based on relating a multimarker...

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PMID: 21308765
DOI: 10.1002/gepi.20567
PMCID: PMC3134543

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