Article
The BMP signaling gradient patterns dorsoventral tissues in a temporally progressive manner along the anteroposterior axis.
Developmental cell - 1 Jan 2008
Tucker Jennifer A, Mintzer Keith A, Mullins Mary C
Abstract excerpt
Patterning of the vertebrate anteroposterior (AP) axis proceeds temporally from anterior to posterior. How dorsoventral (DV) axial patterning relates to AP temporal patterning is unknown. We examined the temporal activity of BMP signaling in patterning ventrolateral cell fates along the AP axis, using transgenes that rapidly turn "off" or "on" BMP signaling. We show that BMP signaling patterns rostral DV cell...
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