Article
Pharmacogenetics in treatment of rheumatoid arthritis.
Current pharmaceutical design - 1 Jan 2010
Kooloos W M, Huizinga T W J, Guchelaar H-J, Wessels J A M
Abstract excerpt
Over the last decades important progress is being made regarding disease modifying anti-rheumatic drugs (DMARDs) in the treatment of rheumatoid arthritis (RA). Nevertheless, a substantial part of the patients fail to achieve a good response and/or experience toxicity, which limits further treatment leading to progression of inflammation and destruction of joints. These high interindividual differences in drug...
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