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Article

Gender effect of catechol-O-methyltransferase Val158Met polymorphism on suicidal behavior.

Neuropsychobiology - 1 Jan 2011

Lee Hwa-Young, Kim Yong-Ku

Abstract excerpt

Genetic factors and catecholaminergic dysfunction have been suggested as the etiology of suicide. The catechol-O-methyltransferase (COMT) 158Val/Met polymorphism affects COMT activity; that is, the alleles encoding Val and Met are associated with relatively high and relatively low COMT activity, respectively. We aimed to identify the role of the COMT Val158Met polymorphism in suicidal attempt behavior. The COMT...

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Source

Identifiers

PMID: 21304229
DOI: 10.1159/000317847

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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