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Article

Catechol-O-methyltransferase polymorphism (COMT) in suicide attempters: a possible gender effect on anger traits.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Dec 2007

Baud Patrick, Courtet Philippe, Perroud Nader, Jollant Fabrice, Buresi Catherine, Malafosse Alain

Abstract excerpt

Anger-related personality traits are considered contributory risk factors for suicidal behavior. According to twin studies, they are partially under genetic control and their various clinical expressions have been associated with serotonergic and catecholaminergic activities. A functional polymorphism on the human catechol-O-methyltransferase (COMT) gene, which codes for the catecholamines inactivating enzyme...

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Source

Identifiers

PMID: 17510945
DOI: 10.1002/ajmg.b.30541

Genes

COMT

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Related research

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Catechol-O-methyltransferase polymorphism (COMT) in suicide attempters: a possible gender effect on anger traits.PMID 17510945Read ↗

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Association study of a functional catechol-O-methyltransferase (COMT) Val108/158Met polymorphism and suicide attempts in patients with alcohol dependence.Semantic proximity Read ↗

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The role of the catechol-O-methyltransferase (COMT) gene in personality and related psychopathological disorders.Semantic proximity Read ↗

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