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Article

Catechol-o-methyltransferase gene modulation on suicidal behavior and personality traits: review, meta-analysis and association study.

Journal of psychiatric research - 1 Mar 2011

Calati Raffaella, Porcelli Stefano, Giegling Ina, Hartmann Annette M, Möller Hans-Jürgen, De Ronchi Diana, Serretti Alessandro, Rujescu Dan

Abstract excerpt

Suicide is one of the leading causes of death among young adults. Both genetic and personality factors plausibly have a role on suicidal behavior. We focused on the catechol-O-methyltransferase gene (COMT) and we performed: a review of studies investigating the association between COMT and both suicidal behavior and personality; a meta-analysis of studies investigating the association between suicidal behavior...

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Source

Identifiers

PMID: 20667552
DOI: 10.1016/j.jpsychires.2010.07.004

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Catechol-o-methyltransferase gene modulation on suicidal behavior and personality traits: review, meta-analysis and association study.PMID 20667552Read ↗

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Meta-analyses suggest association between COMT, but not HTR1B, alleles, and suicidal behavior.Semantic proximity Read ↗

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