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Article

Oral immunization of mice with Lactococcus lactis expressing the rotavirus VP8* protein.

Biotechnology letters - 1 Jun 2011

Rodríguez-Díaz Jesús, Montava Rebeca, Viana Rosa, Buesa Javier, Pérez-Martínez Gaspar, Monedero Vicente

Abstract excerpt

The efficacy of recombinant Lactococcus lactis as a delivery vehicle for a rotavirus antigen was evaluated in a mouse model. The rotavirus VP8* protein was expressed intracellularly and extracellularly in L. lactis wild type and in an alr mutant deficient in alanine racemase activity, necessary for the synthesis of the cell-wall component D: -alanine. When the mucosal immune response was evaluated by measuring...

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Source

Identifiers

PMID: 21302132
DOI: 10.1007/s10529-011-0551-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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