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Article

Recent insights into the genetics of inflammatory bowel disease.

Gastroenterology - 1 May 2011

Cho Judy H, Brant Steven R

Abstract excerpt

Inflammatory bowel diseases (IBDs) are complex, multifactorial disorders that comprise Crohn's disease (CD) and ulcerative colitis (UC). Genome-wide association studies have identified approximately 100 loci that are significantly associated with IBD. These loci implicate a diverse array of genes and pathophysiologic mechanisms, including microbe recognition, lymphocyte activation, cytokine signaling, and...

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Source

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Identifiers

PMID: 21530736
DOI: 10.1053/j.gastro.2011.02.046
PMCID: PMC4947143

Genes

NOD2
REL
SMAD3
STAT3
ZMIZ1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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