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Article

Bimodal distribution of RNA expression levels in human skeletal muscle tissue.

BMC genomics - 7 Feb 2011

Mason Clinton C, Hanson Robert L, Ossowski Vicky, Bian Li, Baier Leslie J, Krakoff Jonathan, Bogardus Clifton

Abstract excerpt

BACKGROUND: Many human diseases and phenotypes are related to RNA expression, levels of which are influenced by a wide spectrum of genetic and exposure-related factors. In a large genome-wide study of muscle tissue expression, we found that some genes exhibited a bimodal distribution of RNA expression, in contrast to what is usually assumed in studies of a single healthy tissue. As bimodality has classically been...

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Identifiers

PMID: 21299892
DOI: 10.1186/1471-2164-12-98
PMCID: PMC3044673

Genes

ACTN3
ERAP2
GSTM1
MAOA
THNSL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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