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Article

MMP1 bimodal expression and differential response to inflammatory mediators is linked to promoter polymorphisms.

BMC genomics - 19 Jan 2011

Affara Muna, Dunmore Benjamin J, Sanders Deborah A, Johnson Nicola, Print Cristin G, Charnock-Jones D Stephen

Abstract excerpt

BACKGROUND: Identifying the functional importance of the millions of single nucleotide polymorphisms (SNPs) in the human genome is a difficult challenge. Therefore, a reverse strategy, which identifies functionally important SNPs by virtue of the bimodal abundance across the human population of the SNP-related mRNAs will be useful. Those mRNA transcripts that are expressed at two distinct abundances in proportion...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 21244711
DOI: 10.1186/1471-2164-12-43
PMCID: PMC3040839

Genes

MMP1
ETS1
ETS2
GATA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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