Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The mitochondrial T16189C polymorphism is associated with coronary artery disease in Middle European populations.

PloS one - 26 Jan 2011

Mueller Edith E, Eder Waltraud, Ebner Sabine, Schwaiger Eva, Santic Danijela, Kreindl Tanja, Stanger Olaf, Paulweber Bernhard, Iglseder Bernhard, Oberkofler Hannes, Maier Richard, Mayr Johannes A, Krempler Franz, Weitgasser Raimund, Patsch Wolfgang, Sperl Wolfgang, Kofler Barbara

Abstract excerpt

BACKGROUND: The pivotal role of mitochondria in energy production and free radical generation suggests that the mitochondrial genome could have an important influence on the expression of multifactorial age related diseases. Substitution of T to C at nucleotide position 16189 in the hypervariable D-loop of the control region (CR) of mitochondrial DNA (mtDNA) has attracted research interest because of its...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Coronary Artery Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to DNA, Mitochondrial

Share to Europe

Share to Genetic Predisposition to Disease

Share to Polymorphism, Single Nucleotide

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 21298061
DOI: 10.1371/journal.pone.0016455
PMCID: PMC3027676

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The mitochondrial T16189C polymorphism is associated with coronary artery disease in Middle European populations.PMID 21298061Read ↗

The mitochondrial DNA variant 16189T>C is associated with coronary artery disease and myocardial infarction in Saudi Arabs.Semantic proximity Read ↗

Analysis of mitochondrial DNA heteroplasmic mutations A1555G, C3256T, T3336C, С5178А, G12315A, G13513A, G14459A, G14846А and G15059A in CHD patients with the history of myocardial infarction.Semantic proximity Read ↗

The role of control region mitochondrial DNA mutations in cardiovascular disease: stroke and myocardial infarction.Semantic proximity Read ↗

The role of control region mitochondrial DNA mutations in cardiovascular disease: stroke and myocardial infarctionSemantic proximity Read ↗

The aetiology of cardiovascular disease: a role for mitochondrial DNA?Semantic proximity Read ↗

Examining the Association between Mitochondrial Genome Variation and Coronary Artery DiseaseSemantic proximity Read ↗

Mitochondrial related variants associated with cardiovascular traitsSemantic proximity Read ↗

Mitochondrial DNA haplogroup T is associated with coronary artery disease and diabetic retinopathy: a case control study.Semantic proximity Read ↗

Mitochondrial mutations in atherosclerosis: new solutions in research and possible clinical applications.Semantic proximity Read ↗

Meta-analysis of mitochondrial T16189C polymorphism for cancer and Type 2 diabetes risk.Semantic proximity Read ↗

Association of mitochondrial deoxyribonucleic acid 16189 variant (T->C transition) with metabolic syndrome in Chinese adults.Semantic proximity Read ↗

Single nucleotide polymorphisms in the mitochondrial control region are associated with metabolic phenotypes and oxidative stress.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.