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Article

The aetiology of cardiovascular disease: a role for mitochondrial DNA?

Cardiovascular journal of Africa - 1 Jan 2000

Venter Marianne, van der Westhuizen Francois H, Elson Joanna L

Abstract excerpt

Cardiovascular disease (CVD) is a world-wide cause of mortality in humans and its incidence is on the rise in Africa. In this review, we discuss the putative role of mitochondrial dysfunction in the aetiology of CVD and consequently identify mitochondrial DNA (mtDNA) variation as a viable genetic risk factor to be considered. We then describe the contribution and pitfalls of several current approaches used when...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28906532
DOI: 10.5830/CVJA-2017-037
PMCID: PMC6009096

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