Article
Association of mitochondrial deoxyribonucleic acid 16189 variant (T->C transition) with metabolic syndrome in Chinese adults.
The Journal of clinical endocrinology and metabolism - 1 Sept 2005
Weng Shao-Wen, Liou Chia-Wei, Lin Tsu-Kung, Wei Yau-Huei, Lee Cheng-Feng, Eng Hock-Liew, Chen Shang-Der, Liu Rue-Tsuan, Chen Jung-Fu, Chen I-Ya, Chen Ming-Hong, Wang Pei-Wen
Abstract excerpt
OBJECTIVE: A common variant in mitochondrial DNA (mtDNA) at bp 16189 (T-->C transition) has been associated with small birth size, adulthood hyperglycemia, and insulin resistance in Caucasians. In this study, we investigated whether mtDNA 16189 variant is associated with metabolic syndrome in Chinese subjects. METHODS: Six hundred fifteen Chinese adults, aged 40 yr or older, were recruited in this study. The...
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