Assessing gene length biases in gene set analysis of Genome-Wide Association Studies.

Abstract excerpt

Genome-Wide Association Studies (GWAS) have rapidly become a major genetics approach to studying complex diseases. Although many susceptibility variants and genes have been uncovered by single marker analysis, gene set based analysis is emerging as a very promising approach aiming to detect joint association of a set of genes with disease. In the available gene set based methods, it is often the smallest P value...

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