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Sample Size Calculation in Genetic Association Studies: A Practical Approach

14 Jan 2023

Abstract excerpt

Genetic association studies, testing the relationship between genetic variants and disease status, are useful tools for identifying genes that grant susceptibility to complex disorders. In such studies, an inadequate sample size may provide unreliable results: a small sample is unable to accurately describe the population, whereas a large sample makes the study expensive and complex to run. However, in genetic...

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PMID: 36676184
DOI: 10.3390/life13010235

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