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Article

Evolutionary context for the association of γ-globin, serum uric acid, and hypertension in African Americans.

BMC medical genetics - 5 Nov 2015

Shriner Daniel, Kumkhaek Chutima, Doumatey Ayo P, Chen Guanjie, Bentley Amy R, Charles Bashira A, Zhou Jie, Adeyemo Adebowale, Rodgers Griffin P, Rotimi Charles N

Abstract excerpt

BACKGROUND: Hyperuricemia and associated cardio-metabolic disorders are more prevalent in African Americans than in European Americans. We used genome-wide admixture mapping and association testing to identify loci with ancestry effects on serum uric acid levels. METHODS: We analyzed 1,976 African Americans from Washington, D.C, including 1,322 individuals from 328 pedigrees and 654 unrelated individuals,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26686224
DOI: 10.1186/s12881-015-0249-z
PMCID: PMC4684912

Genes

HBG1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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