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Article

Blood lead levels, ALAD gene polymorphisms, and mortality.

Epidemiology (Cambridge, Mass.) - 1 Mar 2011

van Bemmel Dana M, Li Yan, McLean Jody, Chang Man-Huei, Dowling Nicole F, Graubard Barry, Rajaraman Preetha

Abstract excerpt

BACKGROUND: Previous analyses from the National Health and Nutrition Examination Survey (NHANES III) have found that elevated blood lead levels may be associated with cardiovascular mortality, cancer mortality, and all-cause mortality. The 5-aminolevulinic acid dehydratase (ALAD) G177C genetic polymorphism (rs 1800435) affects lead toxicokinetics and may alter the adverse effects of lead exposure. We examined...

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Identifiers

PMID: 21293208
DOI: 10.1097/EDE.0b013e3182093f75
PMCID: PMC3932657

Genes

ALAD

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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