Article

MicroRNA-4651 targets bromodomain-containing protein 4 to inhibit non-small cell lung cancer cell growth

2019-12-06

Abstract excerpt

<h4>Background: </h4> Bromodomain-containing protein 4 (BRD4) overexpression in non-small cell lung cancer (NSCLC) is important for cancer cell progression. The aim of the present study is to silence BRD4 through expression of its targeted microRNAs in NSCLC cells. <h4>Methods:</h4> Expression of BRD4 and its targeting miRNA, microRNA-4651 (miR-4651), was tested by qPCR and Western blotting assays. Genetic strateg...

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Literature Corpus work: db1b1bd4-5622-5e85-acfc-550070066c38
DOI: 10.21203/rs.2.18318/v2

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