Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA-145 overexpression inhibits neuroblastoma tumorigenesis in vitro and in vivo

1 Jan 2020

Abstract excerpt

Neuroblastoma (NB) is responsible for 15% of all childhood cancer deaths. Despite advances in treatment and disease management, the overall 5-year survival rates remain poor in high-risk disease (25–40%). It is well known that miR-145 functions as a tumor suppressor in several types of cancer. However, the impact of miR-145 on NB is still ambiguous. Our aim was to investigate the potential tumor suppressive role...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Neuroblastoma Research and Treatments
Share to Signaling Pathways in Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32083506
DOI: 10.1080/21655979.2020.1729928

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA-145 overexpression inhibits neuroblastoma tumorigenesis in vitro and in vivoPMID 32083506Read ↗

MicroRNA-497 increases apoptosis in MYCN amplified neuroblastoma cells by targeting the key cell cycle regulator WEE1Semantic proximity Read ↗

MiR-145 inhibits cell proliferation of human lung adenocarcinoma by targeting EGFR and NUDT1.Semantic proximity Read ↗

MicroRNA-145 inhibits the growth, invasion, metastasis and angiogenesis of neuroblastoma cells through targeting hypoxia-inducible factor 2 alphaSemantic proximity Read ↗

microRNA-145 suppresses lung adenocarcinoma-initiating cell proliferation by targeting OCT4Semantic proximity Read ↗

miR-99b-5p, miR-380-3p, and miR-485-3p are novel chemosensitizing miRNAs in high-risk neuroblastomaSemantic proximity Read ↗

Regulatory mechanisms of miR-145 expression and the importance of its function in cancer metastasisSemantic proximity Read ↗

miR-149 inhibits cell proliferation and enhances chemosensitivity by targeting CDC42 and BCL2 in neuroblastomaSemantic proximity Read ↗

Functional high-throughput screening reveals miR-323a-5p and miR-342-5p as new tumor-suppressive microRNA for neuroblastomaSemantic proximity Read ↗

Dual-strand tumor-suppressor microRNA-145 (miR-145-5p and miR-145-3p) coordinately targeted MTDH in lung squamous cell carcinomaSemantic proximity Read ↗

MiR-145 in cancer therapy resistance and sensitivity: A comprehensive review.Semantic proximity Read ↗

miR-145-5p Inhibits Neuroendocrine Differentiation and Tumor Growth by Regulating the SOX11/MYCN Axis in Prostate cancerSemantic proximity Read ↗

Effects of miR-145-5p through NRAS on the cell proliferation, apoptosis, migration, and invasion in melanoma by inhibiting MAPK and PI3K/AKT pathways.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.