Article
Differentiation of hairbulb pigment cell melanosomes in compound agouti and albino locus mouse mutants (Ay, a, c2J; C57BL/6J).
Pigment cell research - 1 Jan 2000
Granholm N H, Japs R A, Kappenman K E
Abstract excerpt
Our objective was to determine using electron microscopy how nonagouti (a), lethal yellow (Ay), and albino (c2J) genes affect the program of mouse hairbulb melanosome differentiation; 1,921 hairbulb melanosomes from four genotypes (a/a C/C = B,Ay/a C/C = Y, a/a c2J/c2J = BA, and Ay/a c2J/c2J = YA) were scored for developmental stage, length, and width. Qualitative and quantitative electron microscopy revealed the...
Topics
- Albinism
- Analysis of Variance
- Animals
- Cell Differentiation
- Female
- Genes, Lethal
- Genotype
- Hair
- Hair Color
- Male
- Melanocytes
- Mice