Article
The pinkeyed-dilution protein and the eumelanin/pheomelanin switch: in support of a unifying hypothesis.
Pigment cell research - 1 Oct 1995
Lamoreux M L, Zhou B K, Rosemblat S, Orlow S J
Abstract excerpt
The two major types of mammalian melanin are pheomelanin (yellow or red pigment) and eumelanin (black or brown). The agouti (A) and extension (E) loci determine whether follicular melanocytes will deposit pheomelanin or eumelanin within their melanosomes. Mutations at the murine pinkeyed-dilution...
Topics
- Agouti Signaling Protein
- Animals
- Intercellular Signaling Peptides and Proteins
- Intramolecular Oxidoreductases
- Isomerases
- Melanins
- Melanocytes
- Membrane Glycoproteins
- Mice
- Mice, Inbred C57BL
- Models, Biological
- Molecular Weight
- Monophenol Monooxygenase
- Mutation
- Oxidoreductases
- Proteins
- RNA, Messenger
- Skin