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Article

The pinkeyed-dilution protein and the eumelanin/pheomelanin switch: in support of a unifying hypothesis.

Pigment cell research - 1 Oct 1995

Lamoreux M L, Zhou B K, Rosemblat S, Orlow S J

Abstract excerpt

The two major types of mammalian melanin are pheomelanin (yellow or red pigment) and eumelanin (black or brown). The agouti (A) and extension (E) loci determine whether follicular melanocytes will deposit pheomelanin or eumelanin within their melanosomes. Mutations at the murine pinkeyed-dilution (P) locus cause a striking reduction in deposition of eumelanic, but not pheomelanic, pigment. The mRNA encoded at the...

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Identifiers

PMID: 8789201
DOI: 10.1111/j.1600-0749.1995.tb00673.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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