Article
Single-Nucleotide Polymorphisms in IL23R-IL12RB2 (rs1495965) Are Highly Prevalent in Patients with Behcet's Uveitis and Vary Between Populations.
Ocular immunology and inflammation - 1 Jan 2019
Kramer Michal, Hasanreisoglu Murat, Weiss Shirel, Kumova Deniz, Schaap-Fogler Michal, Guntekin-Ergun Sezen, Ozdek Sengul, Gurelik Gokhan, Ergün Mehmet Ali, Goldenberg-Cohen Nitza, Cohen Yoram
Abstract excerpt
Purpose: To test the frequency of single-nucleotide polymorphisms in the IL-10, IL23R-IL12RB2 genes in patients with Behcet's uveitis. Methods: Blood samples were collected from 89 Israeli and Turkish patients, and from healthy control subjects of different origins. Genomic DNA was extracted from peripheral blood leukocytes and genotyped. Results: The risk allele, A, in rs1800871, of IL-10 gene was highly...
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