Article
Conversion from Prograf to Advagraf in adolescents with stable liver transplants: comparative pharmacokinetics and 1-year follow-up.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society - 1 Oct 2013
Carcas-Sansuán Antonio J, Hierro Loreto, Almeida-Paulo Gonzalo N, Frauca Esteban, Tong Hoi Yan, Díaz Carmen, Piñana Enrique, Frías-Iniesta Jesús, Jara Paloma
Abstract excerpt
The recommended dose of Advagraf for conversion from Prograf is considered to be 1:1 on a milligram basis. However, the long-term equivalence of Prograf and Advagraf has been questioned. The relative bioavailability of Advagraf and Prograf was evaluated in a single-center, open-label study of Prograf-to-Advagraf conversion in 20 patients, ranging in age from 12 to 18 years, who had a stable liver transplant and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.