Article
Pharmacokinetics of a once-daily tacrolimus formulation in first nations and caucasian liver transplant recipients.
Transplant international : official journal of the European Society for Organ Transplantation - 1 Nov 2021
Peretz David, On Ngoc H, Miller Donald, Kim Richard, Franklin Carla, Dascal Roman, Knowles Cori, Minuk Gerald Y
Abstract excerpt
Patient ethnicity may influence the pharmacokinetics (PK) of tacrolimus. Because the Canadian First Nations (FN) constitute a large and increasing segment of the liver transplant population, we undertook to determine whether PK differences exist for a once-daily, extended release formulation of tacrolimus (Advagraf) in FN compared to Caucasian (CAUC) liver transplant recipients. Following achievement of a steady...
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