Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alpha-defensin DEFA1A3 gene copy number variation in Asians and its genetic association study in Chinese systemic lupus erythematosus patients.

Gene - 1 Apr 2013

Cheng Fa-juan, Zhou Xu-jie, Zhao Yan-feng, Zhao Ming-hui, Zhang Hong

Abstract excerpt

Neutrophil extracellular traps (NETs) were closely associated with activation of type I interferon (IFN) pathway in systemic lupus erythematosus (SLE). We aimed to study the genetic basis of NETs-DEFA1A3 copy number variations (CNV) in SLE and HapMap CHB+JPT populations by quantitative real-time PCR and whole genome sequences data. DEFA1A3 CNs did not differ significantly between SLE patients and controls....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha-Defensins
Share to Asian People
Share to China

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to Genetic Association Studies

Share to Lupus Erythematosus, Systemic

Share to Peptides, Cyclic

Source

Identifiers

PMID: 23333728
DOI: 10.1016/j.gene.2013.01.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alpha-defensin DEFA1A3 gene copy number variation in Asians and its genetic association study in Chinese systemic lupus erythematosus patients.PMID 23333728Read ↗

Association between FCGR3B copy number variations and susceptibility to autoimmune diseases: a meta-analysis.Semantic proximity Read ↗

Association of β-defensin gene copy number variations with ankylosing spondylitis in Chinese population: A case-control study.Semantic proximity Read ↗

Runaway multi-allelic copy number variation at the α-defensin locus in African and Asian populations.Semantic proximity Read ↗

Low α-defensin gene copy number increases the risk for IgA nephropathy and renal dysfunction.Semantic proximity Read ↗

Low-Copy Number Polymorphism in DEFA1/DEFA3 Is Associated with Susceptibility to Hospital-Acquired Infections in Critically Ill Patients.Semantic proximity Read ↗

Association of FCGR3A and FCGR3B copy number variations with systemic lupus erythematosus and rheumatoid arthritis in Taiwanese patients.Semantic proximity Read ↗

Low copy numbers of FCGR3A and FCGR3B associated with Chinese patients with SLE and AASV.Semantic proximity Read ↗

Higher DEFB4 genomic copy number in SLE and ANCA-associated small vasculitis.Semantic proximity Read ↗

Systemic Lupus Erythematosus Patients with DNASE1L3·Deficiency Have a Distinctive and Specific Genic Circular DNA Profile in PlasmaSemantic proximity Read ↗

Functional single-nucleotide polymorphisms in the DEFB1 gene are associated with systemic lupus erythematosus in Southern Brazilians.Semantic proximity Read ↗

Association study of copy number variants in FCGR3A and FCGR3B gene with risk of ankylosing spondylitis in a Chinese population.Semantic proximity Read ↗

Both copy number and sequence variations affect expression of human DEFB4.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.