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Article

Functional genetic polymorphisms in interleukin-12B gene in association with systemic lupus erythematosus.

Rheumatology international - 1 Jan 2012

Miteva Lyuba D, Manolova Irena M, Ivanova Mariana G, Rashkov Rasho K, Stoilov Rumen M, Gulubova Maya V, Stanilova Spaska A

Abstract excerpt

Genetic polymorphisms in cytokine genes, which influence gene expression, may have an important impact on SLE susceptibility and severity. The aim of this study was to examine the possible influence of two functional polymorphisms in cis-regulatory regions of IL12B gene in the susceptibility and clinical symptoms of SLE in Bulgarian patients. Female SLE patients (n = 141) and 124 healthy women were included in...

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PMID: 20658240
DOI: 10.1007/s00296-010-1547-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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