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Article

Association between divalent metal transport 1 encoding gene (SLC11A2) and disease duration in amyotrophic lateral sclerosis.

Journal of the neurological sciences - 15 Apr 2011

Blasco Hélène, Vourc'h Patrick, Nadjar Yann, Ribourtout Bénédicte, Gordon Paul H, Guettard Yves-Olivier, Camu William, Praline Julien, Meininger Vincent, Andres Christian R, Corcia Philippe

Abstract excerpt

BACKGROUND: Dysregulation of iron homeostasis is one possible pathophysiological mechanism involved in motor neuron degeneration in amyotrophic lateral sclerosis (ALS). SLC11A2 gene encodes the divalent metal transport 1 (DMT1) mediating iron transport in cerebral endosomal compartments. The objective of the study was to analyze DMT1 as a possible risk or modulating factor in sporadic ALS (SALS). METHODS: We...

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PMID: 21276595
DOI: 10.1016/j.jns.2010.12.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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