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Article

Germline mutations of the E-cadherin gene in families with inherited invasive lobular breast carcinoma but no diffuse gastric cancer.

Cancer - 15 Jul 2011

Xie Ze Ming, Li Lai Sheng, Laquet Claire, Penault-Llorca Frédérique, Uhrhammer Nancy, Xie Xiao Ming, Bignon Yves Jean

Abstract excerpt

BACKGROUND: Present data are highly suggestive but do not unequivocally prove the cosegregation of germ-line CDH1 mutations with inherited invasive lobular breast cancer (ILBC). METHODS: Two Caucasian families with 6 pathologically confirmed ILBC cases but no diffuse gastric cancer (DGC) were identified in our oncogenetics consultations. Screening for mutations of CDH1, BRCA1, and BRCA2 genes was performed on...

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Source

Identifiers

PMID: 21271559
DOI: 10.1002/cncr.25876

Genes

CDH1
BRCA1
BRCA2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Germline mutations of the E-cadherin gene in families with inherited invasive lobular breast carcinoma but no diffuse gastric cancer.PMID 21271559Read ↗

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Hereditary Gastric and Breast Cancer Syndromes Related to CDH1 Germline Mutation: A Multidisciplinary Clinical ReviewSemantic proximity Read ↗

Characterization of a Recurrent Germ Line Mutation of the <i>E-Cadherin</i> Gene: Implications for Genetic Testing and Clinical ManagementSemantic proximity Read ↗

Germline E-cadherin mutations in hereditary diffuse gastric cancer: assessment of 42 new families and review of genetic screening criteria.Semantic proximity Read ↗

E-cadherin alterations in hereditary disorders with emphasis on hereditary diffuse gastric cancer.Semantic proximity Read ↗

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